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Regimen for TPT
Learning ObjectivesDiscuss about the two regimens used under TPT.
The following TPT treatment options are recommended under NTEP once active TB has been ruled out:
|
6H |
3HP |
|
|---|---|---|
|
Medicines |
Isoniazid |
Isoniazid + rifapentine |
|
Duration (months) |
6 |
3 |
|
Interval |
Daily |
Weekly |
|
Doses |
182 |
12 |
|
Pregnant women |
Safe for use |
Not Known |
Post-treatment TPT for PLHIV: In patients previously treated for TB, post-treatment TPT has been considered in view of the 5-7 times higher risk of recurrence of TB among PLHIV and nearly 90% of these due to re-infection. Thus, all CLHIV/PLHIV who had successfully completed treatment for TB disease earlier should receive a course of TPT after completing treatment of TB.
Resources
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Guideline for Programmatic Management of Tuberculosis Preventive Treatment in India
-
Latent TB Infection : Updated and Consolidated Guidelines for Programmatic Management, WHO, 2018
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